Molecular mechanisms in the control of gene expression

[proceedings] edited by Donald P. Nierlich, W.J. Rutter, C. Fred Fox.
  • 655 Pages
  • 2.38 MB
  • 1769 Downloads
  • English
by
Academic Press , New York
Gene expression -- Congresses, Molecular genetics -- Congr
SeriesI.C.N.-U.C.L.A. symposia on molecular and cellular biology, v. 5, I.C.N.-U.C.L.A. symposia on molecular and cellular biology -- v. 5
ContributionsFox, C. Fred, I.C.N. Pharmaceuticals, inc., Nierlich, Donald P., Rutter, William J., University of California, Los Angeles.
The Physical Object
Paginationxi, 655 p. ill. ;
ID Numbers
Open LibraryOL19753763M

Molecular Mechanisms in the Control of Gene Expression documents the proceedings of the ICN-UCLA conference on Molecular Mechanisms in the Control of Gene Expression, organized through the Molecular Biology Institute of UCLA, held in Keystone, Colorado, March Assorted mechanisms that include DNA methylation, histone modification, regulatory RNA, and structural continuity, all take part in epigenetic inheritance.

To qualify as truly epigenetic, changes in gene expression must be passed on from one cell to its descendants. In bacteria epigenetics almost always involves DNA methylation.

Purchase Molecular Mechanisms in the Control of Gene Expression - 1st Edition. Print Book & E-Book.

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ISBNBook Edition: 1. The mechanisms that control the expression of genes operate at many levels, and we discuss the different levels in turn. At the end of the chapter, we examine how modern-day genomes and their systems of regulation have been shaped by evolutionary by: Molecular mechanisms in the control of gene expression.

New York: Academic Press, (OCoLC) Online version: ICN-UCLA Conference on Molecular Mechanisms in the Control of Gene Expression, Keystone, Colo., Molecular mechanisms in the control of gene expression. New York: Academic Press, (OCoLC) Material Type. Regulation of Gene Expression: Molecular Mechanisms is intended to serve as either a textbook for graduate students or as a basic reference for laboratory personnel.

Indeed, we are using this book to teach a graduate-level class at The Pennsylvania State : Gary H. Perdew, Jack P.

Details Molecular mechanisms in the control of gene expression FB2

Vanden Heuvel, Jeffrey M. Peters. A detailed knowledge of the mechanisms underlying the transcriptional control of gene expression is of fundamental importance to many areas of contemporary biomedical research, ranging from understanding basic issues (such as control of embryonic development) to practical applications in industry and medicine.

Transcriptional control in eukaryotic cells can be visualized as involving several levels of regulation. The concentrations and activities of activators and repressors that control transcription of many protein-coding genes are regulated during cellular differentiation and in response to hormones and signals from neighboring cells.

These activators and repressors Molecular mechanisms in the control of gene expression book turn regulate Author: Harvey Lodish, Arnold Berk, S Lawrence Zipursky, Paul Matsudaira, David Baltimore, James Darnell.

In Arabidopsis (Arabidopsis thaliana), transcriptional control of seed maturation involves three related regulators with a B3 domain, namely LEAFY COTYLEDON2 (LEC2), ABSCISIC ACID INSENSITIVE3 (ABI3), and FUSCA3 (ABI3/FUS3/LEC2 [AFLs]).

Although genetic analyses have demonstrated partially overlapping functions of these regulators, the Cited by: Despite the significance of modern genetics, many of its fundamentals are still not widely understood. A summary of what has been learned about DNA might serve as a useful introduction to the discussion on transcription and gene expression: The heritable genetic information for all life comes in the form of a molecule called DNA.

Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advanced understanding of the various mechanisms.

Written in an informal and accessible style, Chromatin and Gene Regulation enables the reader to understand the science of this rapidly moving field. Chromatin is a fundamental component in the network of controls that regulates gene expression.

Many human diseases have been linked to disruption of these control processes by genetic or environmental factors, and unravelling the Cited by: This book is the first volume in a new series Progress in Gene Expres­ sion. The control of gene expression is a central-most topic in molecular biology as it deals with the utilization and regulation of gene informa­ tion.

The OHOLO Conferences have been convened annually from the Spring of ; the wide areas they have covered, from different and overlapping disciplines, can be seen from the following list: Bacterial Genetics (not published) Tissue Cultures in Virological Research (not published) Inborn and Acquired Resistance to Infection in Animals (not.

Recently, Oct4 has been shown to control and activate the expression of another type of noncoding RNA, the large intergenic noncoding RNAs. Interestingly, knockdown of the expression of such RNAs caused growth defects and apoptosis, implying that these noncoding RNAs are involved in self-renewal and reprogramming of stem cells [ ],[ ].Cited by: 2.

An inducible gene is a gene that is expressed in the presence of a substance (an inducer) in the environment. This substance can control the expression of one or more genes (structural genes) involved in the metabolism of that substance.

For example, lactose induces the expression of the lac genes that are involved in lactose metabolism. Molecular studies of the function of the mammalian retina, including mechanisms that control signal transduction and tissue-specific gene expression in.

These specific proteins, in the form of specific enzymes control specific function, characteristic of that gene. This concept of one way flow of genetic information from DNA to a specific protein is known as Central Dogma of molecular biology-a term coined by Francis Crick (Fig.

Changes in gene expression constitute the main component of the bacterial response to stress and environmental changes, and involve a myriad of different mechanisms, including (alternative) sigma factors, bi- or tri-component regulatory systems, small non-coding RNA’s, chaperones, CHRIS-Cas systems, DNA repair, toxin-antitoxin systems, the.

Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect. The cellular processes that control the rate and manner of gene expression.

Gene expression Gene expression is the process by which the genetic code - the nucleotide sequence - of a gene is used to direct protein synthesis and produce the structures of the cell.

Genes that code for amino acid sequences are known as 'structural genes'. The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology.

Each chapter will review key terms, test for understanding basic concepts, and pose research-based problems. The Problems Book has.

Description Molecular mechanisms in the control of gene expression PDF

Chromatin is a fundamental component in the network of controls that regulates gene expression. Many human diseases have been linked to disruption of these control processes by genetic or environmental factors, and unravelling the mechanisms by which they operate is one of the most exciting and rapidly developing areas of modern biology.

Control of gene expression: An overview of gene control: DNA-binding motifs in gene: Regulatory proteins: How genetic switches work: Chromatin structure and the control of gene expression: The molecular genetic mechanisms that create specialized cell types: Posttranscriptional controls: Membrane structure: The lipid bilayer: Membrane proteinsCited by: 7.

Molecular Cell Biology Lodish 8th Edition Pdf Free. Molecular Cell Biology Lodish 8th Edition Biology is a science fundamentally different from physics or chemistry, which deals with unchanging properties of matter that can be described by mathematical equations.

Biological systems, of course, follow the rules of chemistry and physics, but biology is a historical science. A Genetic Switch: Gene Control and Phage A.

Mark Ptashne. Cell Press, Cambridge, MA, and Blackwell Scientific, Palo Alto, CA, pp., illus. $ PB. A small, easily digestible new textbook, A Genetic Switch, is destined to become an essential primer for novices in molecular biology and a rewarding recapitulation for old hands.

The book builds. studies the molecular mechanisms by which environments can trigger or block genetic expression Epigenetic Marks organic methyl molecules attached to a part of a DNA strand; trigger or block genetic expressions.

Except for one area of gene expression control, plant research has significantly fallen behind studies in insects and vertebrates. The advances made in animal gene expression control have benefited plant research, as we continue to find that much of the machinery and mechanisms controlling gene expression have been preserved in all eukaryotes.

thereby repress gene expression. In eukaryotic organisms, with their very large number of genes (approximately 40 in mammals), this means that the ground state of gene expression is for genes to be turned off. Activation of gene expression requires that cells alleviate nucleosome-mediated repression of an appropriate subset of genes.

ThisFile Size: KB. Gene expression is the process by which information from a gene is used in the synthesis of a functional gene products are often proteins, but in non-protein-coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional expression is summarized in the Central Dogma first formulated by Francis Crick in.

field that studies the molecular mechanisms by which environments trigger genetic expression; the study of influences on gene expression that occur without DNA change Evolutionary psychologists focus on what makes us so alike as humans; study the evolution of behavior and the mind using principles of natural selection.

In the last 15 years, knowledge of the molecular and genetic mechanisms that underlie floral induction, floral patterning, and floral organ identity has exploded.

Elucidation of basic mechanisms has derived primarily from work in three dicot species: Antirrhinum majus, Arabidopsis thaliana, andCited by: control of gene expression 7 an overview of gene control dna-binding motifs in gene regulatory proteins how genetic switches work the molecular genetic mechanisms that create specialized cell types posttranscriptional controls how genomes evolve